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PROJECT OVERVIEW

Create bioengineered bile ducts to be used in liver transplant and congenital biliary diseases.

PROJECT BACKGROUND

The possibility of producing bioengineered extrahepatic bile ducts of various lengths (up to 7-8 cm) will have a major impact on the current transplant and HPB surgical techniques. This is particularly important in the case of a “split-liver” transplant, i.e. when a large donor liver is split in two to be transplanted in two recipients and in the surgery of congenital biliary disease such as biliary atresia and Alagille syndrome.